Plain-English translation of NCT06164561 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Myelofibrosis is a condition where scar tissue builds up in your bone marrow, making it harder for your body to produce healthy blood cells. Right now, doctors diagnose it by doing a painful bone marrow biopsy, and they can't easily repeat it to see how the disease is changing. This study is testing whether two new imaging scans—called 18F-FDG PET/CT and 18F-FAPI PET/MRI—can give doctors a clearer, less invasive picture of what's happening in your bone marrow and how well your treatment is working.
Current imaging methods don't work as well as doctors need them to, especially as the disease progresses. This study exists to find better ways to diagnose and track myelofibrosis without repeated painful biopsies, so doctors can monitor how you're responding to treatment more easily.
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You would come for imaging appointments where you'll receive two advanced scans to visualize what's happening in your bone marrow. The study team will compare these scan results with your bone marrow biopsy results and your medical information to see whether the scans can accurately track your disease. You'll also be followed over time to see how the imaging results connect to how well you do with your treatment.
AI-generated summary from trial data · Aug 31, 2026 · Not medical advice
China
Sponsor
First Affiliated Hospital of Zhejiang University
Collaborators
Zhejiang Provincial Tongde Hospital, Second Affiliated Hospital, Zhejiang University, School of Medicine
Enrollment target
~57 participants
Started
November 2023
Primary completion
December 2026
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in February 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jie Sun, MD，Ph.D
Zhejiang University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.