Plain-English translation of NCT06165302 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a personalized exercise program can help men with metastatic castration-resistant prostate cancer — a type of advanced cancer that has stopped responding to standard hormone therapy. You would work with trainers to follow a 12-week plan that combines resistance exercises and aerobic activity. The researchers want to see if exercise can reduce a type of cancer cell (called circulating tumor cells, or CTCs) that appears in the blood.
Men with advanced prostate cancer that no longer responds to hormone therapy have limited treatment options. Early research suggests that exercise might help slow cancer progression and improve outcomes, but this hasn't been thoroughly tested in this patient group yet.
You likely qualify if…
You likely don't qualify if…
You would commit to a 12-week exercise program tailored specifically for you, meeting with exercise specialists who will guide you through resistance and aerobic activities. You'll visit the clinic at baseline, Week 5, and Week 9 for assessments and adjustments to your program, and you'll keep a diary of your activities. The team will also check in on your health for one year after the program ends.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
United States
Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Collaborators
Physical Medicine & Rehabilitation Educ Research Foundation, Inc
Enrollment target
~20 participants
Started
October 2025
Primary completion
March 2029
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in October 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Rana Sullivan, RN
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.