Plain-English translation of NCT06168786 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Colorectal Cancer research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether —an immunotherapy drug that helps your immune system fight cancer—works better when combined with (a targeted cancer medication) and a focused radiation therapy called SBRT. The study is designed for people with advanced colorectal cancer that has stopped responding to at least two standard chemotherapy treatments. Researchers want to see if this three-part combination can shrink tumors and help people live longer.
Most people with advanced colorectal cancer eventually stop responding to standard chemotherapy drugs, leaving them with few options. This trial is testing whether combining a newer immunotherapy approach with other treatments might help people whose cancer has become resistant to the usual medicines.
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You would receive the immunotherapy medication as an infusion, take as an oral tablet, and undergo a specialized radiation therapy called SBRT targeted at your cancer. This is a 40-person study at multiple centers in China, so you would need to attend regular clinic visits for treatment, blood tests, and imaging scans to see how your cancer responds. The trial will track your health and any side effects you experience throughout the treatment period.
AI-generated summary from trial data · Jul 3, 2026 · Not medical advice
China