Plain-English translation of NCT06169137 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers studied whether eating all your food within just 6 hours a day — and fasting for 18 hours — could reduce inflammation in the body by changing how it makes ketones (a special fuel your body creates during fasting). The study compared this shorter eating window to a more typical 12-hour eating window, and measured changes in immune cells and metabolic markers in women.
Intermittent fasting appears to have anti-inflammatory benefits, but scientists don't fully understand the mechanism — particularly whether ketones are responsible. This study was designed to clarify how time-restricted eating affects the body's chemistry and immune system, and whether these effects differ between women of different body weights.
Participants were admitted to the research facility and followed two different eating patterns: one where they ate all their food within a 6-hour window each day (fasting for 18 hours), and another where they spread meals across 12 hours. Over three days on each schedule, researchers measured ketone production, collected blood samples to analyze immune cells, and tracked other metabolic markers. The study included assessments of appetite, stress, and digestive comfort.
AI-generated summary from trial data · Jul 16, 2026 · Not medical advice
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