Plain-English translation of NCT06169163 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are investigating whether certain chemical compounds in your breath could serve as a simple, non-invasive way to detect squamous cell carcinoma of the esophagus (a type of throat cancer). The study compares breath samples from people diagnosed with this cancer to breath samples from people without cancer, looking for patterns or 'biomarkers' that might help doctors identify the disease earlier in the future.
Currently, detecting esophageal cancer often requires invasive procedures like endoscopy. If breath samples could reliably identify this cancer, doctors might be able to screen for it more easily and catch it at an earlier, more treatable stage.
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You will visit the research clinic once and be asked to breathe into special single-use collection bags twice. The breath samples are transferred onto special tubes using a gentle pump, and a blank air sample is also collected for comparison. The tubes are then sent to Imperial College London for analysis. The entire process takes a short amount of time and is completely non-invasive—no needles, no procedures, just breathing.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
United Kingdom