Plain-English translation of NCT06170229 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial compared two different supervised exercise programs for people with knee osteoarthritis who also had at least one risk factor for heart disease. Researchers wanted to see whether a high-intensity interval training program was more effective than a neuromuscular exercise program at reducing heart disease risk, and whether both programs worked equally well at improving knee symptoms.
People with knee arthritis often have heart disease risk factors like high blood pressure or excess weight. This trial was designed to find out whether a more intense exercise approach might help protect the heart while also treating the knee pain, compared to the standard neuromuscular exercise approach.
Participants were randomly assigned to one of two exercise groups. One group attended one hour of education followed by 12 weeks of supervised high-intensity interval training three times per week. The other group attended two hours of education and then 8 weeks of supervised neuromuscular exercise two times per week. Both programs were delivered by qualified instructors and included regular supervision and monitoring throughout the study period.
AI-generated summary from trial data · Jun 23, 2026 · Not medical advice
Denmark
Sponsor
Frederiksberg University Hospital
Enrollment target
~150 participants
Started
February 2024
Primary completion
March 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in June 2026.