Plain-English translation of NCT06173401 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing two different ways to deliver stereotactic radiosurgery (a precise, targeted form of radiation therapy) to treat cancer that has spread to your spine. You would be randomly assigned to receive either one large dose of radiation in a single treatment session, or the same total dose split into two smaller sessions over a few days. The study wants to find out which approach gives better long-term control of the cancer with fewer side effects.
Doctors know that stereotactic radiosurgery works well for spine cancer, but they aren't sure whether giving it all at once or splitting it into smaller doses over time is better for patients. This trial will help answer that question so future patients can receive the safest and most effective treatment.
You likely qualify if…
You likely don't qualify if…
If you join this trial, you will first have imaging scans (MRI or CT) to plan your treatment. Then you will be randomly assigned to one of two groups: either one radiation treatment session delivering the full dose, or two radiation sessions a few days apart, each delivering half the dose. You will need to come to the treatment center for your assigned sessions and likely have follow-up visits to monitor how well the treatment is working and check for any side effects.
AI-generated summary from trial data · Aug 5, 2026 · Not medical advice
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