Plain-English translation of NCT06181513 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
Researchers want to know whether probiotics—beneficial bacteria taken as a daily capsule—might help slow memory loss or improve thinking in people with mild Alzheimer's disease. You'll take either the probiotic or a placebo (a dummy pill that looks identical) every day for 16 weeks. The study will check your blood markers, brain activity, memory, and gut bacteria to see if the medication makes a difference.
Some research suggests that the bacteria in your gut may affect brain health and memory. This study exists to see whether this medication could be a simple, safe way to support thinking and memory in people with early-stage Alzheimer's disease.
You likely qualify if…
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You will take one capsule by mouth each day for 16 weeks—either containing probiotics or a placebo. The researchers will measure your blood inflammation levels, test your memory and thinking, check your brain activity, and analyze your gut bacteria at different time points. You may also answer questions about your diet and daily habits to help the team understand how the treatment works.
AI-generated summary from trial data · Jul 1, 2026 · Not medical advice
Cyprus
Sponsor
University of Nicosia
Collaborators
Cyprus Institute of Neurology and Genetics
Enrollment target
~40 participants
Started
December 2022
Primary completion
July 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
65 Years – 85 Years
Last updated on clinicaltrials.gov in December 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Nicoletta Nicolaou
University of Nicosia
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.