Plain-English translation of NCT06183437 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
Some cancer treatments can damage the heart, so doctors prescribe heart-protective medications like beta-blockers and ACE inhibitors to help it recover. In most patients, the heart function returns to normal within months. This trial tests whether patients can safely stop these medications once their heart has healed, or whether it's safer to keep taking them long-term.
Cancer survivors often ask their doctors if they can stop heart medications once their heart function improves, because the medications can cause side effects and cost money. Right now, there's no clear scientific evidence about whether it's safe to stop—so this study aims to find the answer.
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You will be randomly assigned to either stop your heart medications gradually (under close medical supervision) or continue taking them as normal. You'll have heart imaging scans at the beginning, after 1 year, and after 5 years, plus safety check-ins at 6-8 weeks, 6 months, and at 3 and 5 years. The study lasts 5 years total and will help determine if stopping the medication is just as safe as continuing it.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
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