Plain-English translation of NCT06184126 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Sickle Cell Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This pilot study is testing whether virtual reality headsets can help people with sickle cell disease manage severe pain during a vaso-occlusive crisis—a painful blockage of blood vessels that is a common complication of the disease. Participants will use one of two types of virtual reality experiences while receiving their usual emergency care, and researchers will measure how much the virtual reality helps reduce pain and the amount of opioid medications needed.
Sickle cell disease causes severe, unpredictable pain crises that often require large doses of opioid medications in the emergency room. Researchers want to see if this treatment can provide a safe, non-medication way to help manage pain and potentially reduce the need for strong painkillers.
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If you enroll, a research team member will interview you and collect information about your symptoms. You will then use a virtual reality headset for up to 2 hours while in the emergency department—either with an interactive experience where you can control what you see and do, or with a passive experience where you watch a preset scene. The research team will ask you to rate your pain on a 0-10 scale at four different times: before, at the 1-hour mark, immediately after, and 1 hour after using the headset. At the end, you will answer questions about your experience.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
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