Plain-English translation of NCT06185686 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study follows young patients with newly diagnosed brain tumors who are receiving proton radiation therapy — a targeted form of radiation treatment. Researchers will use special brain imaging scans to see how radiation affects the way different areas of your brain communicate with each other. The goal is to understand why some patients experience memory and thinking problems after treatment, so doctors can better predict and prevent these issues in the future.
While modern treatments have helped more young patients survive brain tumors, many experience thinking and memory problems afterward that affect their independence and quality of life. This trial exists to understand how radiation causes these brain changes and to identify warning signs early, so doctors can develop ways to protect brain function during and after treatment.
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You will have special brain imaging scans (MRI) before radiation therapy and then at several time points after treatment begins. During these scans, you'll rest quietly inside the MRI machine while it takes pictures of how your brain networks are working. The study involves about 16 young patients total, and researchers will track changes in your brain function over time to see how the radiation affects the way your brain's different regions communicate.
AI-generated summary from trial data · Jul 22, 2026 · Not medical advice
United States