Plain-English translation of NCT06186869 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether two different types of exercise—combined with a Mediterranean diet focused on low-glycemic foods—can help reduce inflammation and improve liver health in people with obesity and fatty liver disease. You would be randomly assigned to one of three groups: moderate-intensity walking, high-intensity interval training in a gym, or diet alone. The study lasts 4 months and measures changes in inflammation markers, body composition, fitness, and quality of life.
Fatty liver disease (NAFLD) is increasingly common in people with obesity, and inflammation plays a key role in its progression. Researchers want to know whether combining exercise with a healthy Mediterranean diet can reduce that inflammation better than diet alone, and whether the type or intensity of exercise matters.
You likely qualify if…
You likely don't qualify if…
You'll be assigned to one of three groups: one group walks outdoors for 60 minutes, 4 times per week; another does high-intensity interval training in a gym 3 times per week for 50 minutes; and a third follows the diet alone. All participants follow the same Mediterranean diet plan with guidance from nutritionists and exercise specialists. The program runs for 4 months, and researchers will measure your inflammation levels, body composition, fitness, and quality of life through blood tests, scans, and questionnaires.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Italy