Preventing breathing problems in newborns before birth

This trial is testing whether antenatal corticosteroids (a medication given to pregnant women) can help prevent severe breathing problems in newborns. Researchers have developed a prediction model that identifies pregnancies at very high risk for this complication, and this study evaluates whether giving the medication to these high-risk mothers can prevent the problem from occurring in their babies.

Severe breathing problems are a serious complication for newborns, especially those at high risk. While this medication has traditionally been used to help develop fetal lungs, this trial explores a new way it might help—by improving how fluid is cleared from the baby's lungs—and tests whether identifying at-risk pregnancies early and treating them can prevent this breathing problem altogether.