Plain-English translation of NCT06188806 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether the location of a nerve block injection—a numbing treatment given during knee replacement surgery—affects how well it controls pain and helps you move afterward. Researchers will compare two different injection sites (higher up or lower down in the thigh) and a control group that receives standard care, all while you're having knee replacement surgery under spinal anesthesia.
After knee replacement, managing pain well is crucial so you can start moving and exercising to recover properly. This trial is looking for the best location to place a nerve block injection to maximize pain relief and help you regain function faster after surgery.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to one of three groups: receiving a nerve block injection at a higher location in the thigh, a lower location in the thigh, or standard care without the nerve block. The injection is given using ultrasound guidance while you're under spinal anesthesia during your knee replacement surgery. After surgery, researchers will monitor your pain levels and ability to move, comparing how well each approach works.
AI-generated summary from trial data · Jul 20, 2026 · Not medical advice
Turkey (Türkiye)
Sponsor
Umraniye Education and Research Hospital
Enrollment target
~78 participants
Started
November 2023
Primary completion
February 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 85 Years
Last updated on clinicaltrials.gov in November 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Zeliha TUNCEL
Umraniye Education and Research Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.