Plain-English translation of NCT06189755 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are looking for specific biological markers called microRNAs in blood samples that could help doctors better identify obstructive sleep apnea and predict how well people will respond to treatment. MicroRNAs are tiny molecules in your blood that change when your body isn't getting enough oxygen during sleep. By studying these markers in people with and without sleep apnea, scientists hope to develop a simple blood test that could make diagnosis easier and help predict which treatments will work best for each person.
Right now, sleep apnea is hard to diagnose early because there's no simple blood test — doctors rely on overnight sleep studies, which take time and aren't always accessible. This research could eventually lead to a quick blood test that helps doctors catch sleep apnea sooner and predict who will benefit most from their treatment.
You likely qualify if…
You likely don't qualify if…
If you qualify, you'll be asked to donate blood samples that researchers will analyze for these biological markers. Depending on which group you're in (people with sleep apnea or people without), you may also have a sleep study if one hasn't been done recently. The study involves about 500 participants total, and the main time commitment is the blood draw and any necessary sleep testing — there are no medications to take or ongoing treatment requirements for this research.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States
Iceland
Sponsor
University of Pennsylvania
Collaborators
National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI)
Enrollment target
~500 participants
Started
April 2024
Primary completion
November 2027
Age range
18 Years – 75 Years
Last updated on clinicaltrials.gov in July 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Colleen M Walsh, MS
University of Pennsylvania
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.