Plain-English translation of NCT06189976 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
After you receive a transcatheter aortic valve replacement (TAVI) — a minimally invasive procedure to fix a narrowed aortic valve — some patients need a permanent pacemaker implanted to help their heart's electrical system work properly. This trial is testing whether a quick, non-invasive test called rapid atrial pacing can accurately predict which patients will need that pacemaker, potentially helping doctors make better decisions about your care.
Currently, doctors cannot reliably predict who will need a pacemaker after valve replacement, which means some patients may have unnecessary surgery or others may not get the device they need. This test could provide a simple, practical way for all hospitals to identify at-risk patients right after the procedure, without needing specialized equipment or expertise.
You likely qualify if…
You likely don't qualify if…
During your transcatheter aortic valve replacement procedure, doctors will place a temporary pacemaker lead (a thin wire used during the procedure anyway). After the valve is replaced, they will perform a rapid atrial pacing test — essentially pacing your heart at increasing speeds through that temporary lead to see how your heart's electrical system responds. This test takes only a few minutes and uses equipment already in the catheterization lab. You will then be followed up according to standard care, and the research team will track whether you ultimately need a permanent pacemaker.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
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