Plain-English translation of NCT06193252 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a smartphone app can help you move more and stay more active in your daily life over two years. You'll be part of a study designed for people who have been diagnosed with REM sleep behavior disorder (a sleep condition where people act out their dreams), which puts you at higher risk of developing Parkinson's disease later. The study wants to see if increasing your physical activity early on—before any Parkinson's symptoms appear—might slow down or even prevent the disease from developing.
Parkinson's disease is growing faster than other brain diseases, and current treatments haven't been able to slow it down once it's fully developed. This trial is testing whether starting an exercise program much earlier—in people who show early warning signs but don't have Parkinson's yet—could be more effective at preventing the disease altogether.
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You will use a smartphone app for 24 months that tracks and encourages you to increase your daily steps and physical activity. The app will give you personalized goals—some participants will be asked to increase activity significantly, while others will have smaller increases to compare results. Throughout the study, you'll complete digital health assessments on your phone, wear a fitness tracker, and may have brain scans and blood tests to measure changes in your brain health and biomarkers.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
Netherlands