Plain-English translation of NCT06195059 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →Researchers want to test whether a special type of heart ultrasound — one that uses safe contrast dye — can accurately measure blood volume in your lungs during exercise. This measurement could help doctors understand heart and lung problems without needing invasive catheters. The study compares how blood volume changes during exercise in people with and without heart failure.
Currently, doctors sometimes need to insert tubes into blood vessels to measure pressure in the lungs during exercise — a procedure that carries some risk. This research aims to find a safer, non-invasive ultrasound method that could give doctors the same useful information.
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You will undergo heart ultrasound imaging with contrast dye while exercising (likely on a stationary bike or treadmill) at the same time you are having your planned heart catheterization procedure. The ultrasound images will be taken during rest and at different exercise intensities to measure how blood volume in your lungs changes. This allows researchers to compare the ultrasound measurements with the catheterization data to see if ultrasound is accurate enough to replace the invasive procedure in the future.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
United States
Sponsor
Mayo Clinic
Enrollment target
~800 participants
Started
July 2024
Primary completion
November 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in August 2025.
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Central contact
Barry Borlaug, MD
Mayo Clinic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.