Plain-English translation of NCT06206707 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing faecal microbiota transplantation (FMT)—a treatment where capsules containing healthy bacteria from a donor's stool are given to patients—to treat severe diarrhea caused by immune checkpoint inhibitor cancer drugs. People with melanoma or kidney cancer sometimes develop serious diarrhea when taking these medications. This study will see if this treatment can help restore gut health and reduce these side effects.
Immune checkpoint inhibitor drugs are powerful cancer treatments, but they can trigger severe, painful diarrhea and colon inflammation in some patients. Researchers want to know if restoring healthy gut bacteria through this medication can safely reduce these side effects and help patients continue their cancer treatment.
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If you join this study, you will receive two applications of capsules about 3 to 7 days apart—either the active treatment or a placebo (inactive capsule). You'll be randomly assigned to either group, and neither you nor the research team will know which you received. The study will track your diarrhea symptoms and overall health to see if the treatment works and is safe.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
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