Plain-English translation of NCT06207383 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial compares two different catheter procedures to treat people with persistent atrial fibrillation (an irregular heartbeat) and heart failure. One approach focuses on ablating the irregular heart tissue itself, while the other involves implanting a special pacing device and disabling a specific conduction pathway. The study aims to determine which approach works better at reducing hospital visits and improving survival in patients who haven't improved with medication.
Many patients with both irregular heartbeat and heart failure continue to struggle despite taking multiple medications. Doctors need to know whether fixing the heart rhythm directly is better than using a pacemaker-based approach for these complex patients.
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You will be randomly assigned to receive one of two catheter procedures: either an ablation focused on isolating the irregular heart tissue, or a procedure that implants a special pacing system while disabling a conduction pathway in your heart. The study will follow you for 4 years, with regular hospital visits and monitoring to track your heart function, hospitalizations, and overall health. Both procedures are performed by specialists at experienced centers across Europe.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
Austria
Belgium
Bulgaria
Czechia
Finland