Plain-English translation of NCT06207591 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a device called the CortiCom system—a brain implant with special sensors placed on the parts of your brain that control movement and speech. The device is designed to pick up signals from your brain and convert them into commands that let you communicate, even if your body is completely paralyzed. Researchers hope this technology will help people with locked-in syndrome and similar conditions regain meaningful communication with caregivers and loved ones.
People with locked-in syndrome or severe paralysis often lose the ability to speak and move, even though their minds remain fully aware. Current communication aids are limited and often slow. This trial exists to test whether a more advanced brain implant—with more sensors placed in better locations—can provide faster, more reliable communication and dramatically improve quality of life.
You likely qualify if…
You likely don't qualify if…
If you qualify and join this trial, you will undergo brain surgery to have the CortiCom implant placed. Before surgery, you will have detailed brain imaging and medical evaluations to ensure you are a safe surgical candidate. After implant placement, you will work with the research team to learn how to use the device to control basic functions like calling a caregiver and making menu selections, then progress to using a speech-based communication system. You will attend regular visits at University Medical Center Utrecht to test the device and adjust its settings as needed.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
Netherlands