Plain-English translation of NCT06214065 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers are testing whether a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) can affect how a specific brain region involved in social thinking works in autistic adults. The study uses brain imaging before and after TMS sessions to measure whether the stimulation changes brain activity, and compares responses in autistic participants to non-autistic volunteers to understand how the brain differs between the two groups.
Autism affects how people process social information, and there are very few effective treatments to help with social communication skills. This research aims to understand whether targeting a specific brain region with magnetic stimulation could be a new way to help—but first, researchers need to understand exactly how the brain responds to this treatment.
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You would come in for four study visits over several weeks. At each visit (except the first baseline), you'll have a brain scan, receive one type of magnetic brain stimulation, and have another brain scan afterward. During the brain scans, you'll play a competitive game called Domino that involves thinking about what other people are thinking. The three active stimulation sessions will use different types of stimulation (one to increase brain activity, one to decrease it, and one fake/sham treatment), and neither you nor the researchers will know which is which until the study ends.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
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