Plain-English translation of NCT06216899 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Crohn Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether exclusive enteral nutrition — a special diet where you consume only nutritional shakes or smoothies for 8 weeks — can help treat newly diagnosed Crohn's disease in young people. You would be randomly assigned to either prepare home-blended smoothies using a recipe and blender provided by the study, or to use a commercial medical formula provided by the study team. The study will measure how well you tolerate the treatment, how much your Crohn's disease improves, and how it affects your quality of life.
Exclusive enteral nutrition is already known to help calm down Crohn's disease inflammation, but most patients find the commercial formula unpleasant to drink. This trial is trying to find out whether using whole foods blended at home could work just as well while being easier and more enjoyable for young patients to stick with.
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You will participate in this study for 8 weeks total. You will be randomly assigned to either the smoothie group or the formula group. If you're in the smoothie group, you'll receive a blender, detailed recipes, and all the food components you need to prepare nutritional smoothies at home — these will be your main source of nutrition for 8 weeks. If you're in the formula group, you'll receive commercial medical formula from the study team. Throughout the 8 weeks, the research team will check in with you to see how well you're tolerating the nutrition plan, test your inflammation levels, and ask about your quality of life and symptoms.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
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