Plain-English translation of NCT06218433 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Lynch syndrome is an inherited genetic condition that significantly increases your lifetime risk of developing certain cancers, including bladder and upper urinary tract cancers. This trial is testing a new screening approach using urine samples to detect these cancers early—before symptoms develop—when treatment is most likely to be successful. The study will help determine whether this urine-based screening method can benefit people like you who carry Lynch syndrome.
People with Lynch syndrome face a much higher risk of bladder cancer than the general population, yet there are currently no proven early screening methods to catch these cancers at a treatable stage. This study exists to see whether this new approach can identify cancers early enough to make a real difference in outcomes.
You likely qualify if…
You likely don't qualify if…
You will be invited to participate in cancer screening and complete questionnaires about your health. The study involves providing urine samples and answering questions; the exact number of visits and timeline will be explained when you join. This is a screening study, so you won't be taking any medication—instead, you'll help researchers test whether this urine-based approach can effectively catch cancer early in people with your genetic condition.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
Canada
Finland
Sponsor
Tampere University Hospital
Collaborators
Tampere University
Enrollment target
~200 participants
Started
April 2023
Primary completion
December 2026
Age range
50 Years – 75 Years
Last updated on clinicaltrials.gov in November 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jussi Nikkola, MD, PhD
Tampere University Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.