Plain-English translation of NCT06220721 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
The REPAIR trial is testing whether starting treatment with nifedipine extended-release earlier and at lower blood pressure levels in the first six weeks after delivery can prevent chronic high blood pressure from developing. This study focuses on women who experienced high blood pressure during pregnancy—a condition that puts them at higher risk of developing lasting hypertension. Researchers want to see if more aggressive treatment in this critical early postpartum period can protect your heart health long-term.
Women who have high blood pressure during pregnancy are at significantly increased risk of developing chronic high blood pressure later in life. This trial exists to test whether treating blood pressure more aggressively right after delivery—when your body is still adjusting—might prevent this long-term problem and protect your cardiovascular health.
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You would be randomly assigned to either a treatment group or a standard care group for the first six weeks after delivery. The treatment group takes the medication at lower blood pressure thresholds than the standard care group. All participants have their blood pressure monitored regularly and return for visits at six weeks and one year postpartum, where heart function is assessed with ultrasound, blood vessel function is tested, and blood samples are collected to measure heart health markers.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
United States