Recruiting

Home monitoring smartphone app for advanced liver cirrhosis patients

Plain-English translation of NCT06223893 on ClinicalTrials.gov ↗ · Source last updated May 2026 · Translation generated September 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

The CirrhoCare trial is testing a new smartphone-based monitoring system designed to help patients with advanced cirrhosis (severe scarring of the liver) stay safer and out of the hospital. Instead of requiring frequent trips to the hospital for check-ups, the system lets you measure your vital signs like heart rate and blood pressure at home using inexpensive devices, weigh yourself on a smart scale, and complete brief mental health checks on your phone—all of which are important warning signs as liver disease progresses. A specialist doctor uses all this information to provide personalized treatment and catch problems early.

Advanced cirrhosis is a serious condition where one in four patients can suddenly get worse and need emergency hospital care, often within weeks of leaving the hospital. The current healthcare system struggles to provide enough specialist care for all cirrhosis patients, especially because demand is growing. This new treatment aims to help doctors catch problems earlier and manage your care from home, reducing hospital visits and improving access to specialized liver care.

Do you qualify?

You likely qualify if…

you are 18 years old or older
you have been diagnosed with cirrhosis of the liver (of any cause)
you have recently been hospitalized for complications such as fluid buildup, bleeding, confusion, infection, or kidney problems related to your cirrhosis
you have a cirrhosis severity score that falls in a specific range determined by your doctors at the screening visit
you are able to understand and give informed consent to participate in the study

You likely don't qualify if…

you have very severe liver failure (ACLF grade 2 or higher, or a very high severity score)
you currently have severe confusion or altered mental state from liver disease that prevents you from understanding the study
you have active or recently treated cancer (liver cancer or cancer elsewhere in your body)
you have other serious medical conditions that would likely affect your health in the short term, such as severe heart failure, advanced lung disease, or severe kidney disease
you are currently on a liver transplant waiting list or on palliative end-of-life care

What participation looks like

If you join this trial, you will be randomly assigned to either use the new CirrhoCare smartphone monitoring system or receive standard hospital-based care. If you're in the monitoring group, you'll use low-cost devices at home to track your heart rate, blood pressure, and weight, and complete brief mental ability checks on your smartphone—data that your liver doctor reviews regularly to guide your treatment and catch any problems early. Your participation will help researchers determine whether this approach is safer, more convenient, and more cost-effective than traditional hospital visits for managing advanced cirrhosis.

AI-generated summary from trial data · Sep 24, 2026 · Not medical advice

Trial locations(15 sites)

United Kingdom

Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Birmingham

Royal Sussex County Hospital, University Hospitals Sussex NHS Foundation Trust, Brighton

Walsgrave General Hospital, University Hospital Coventry & Warwickshire NHS Trust, Coventry

Royal Liverpool University Hospital, Liverpool University Hospitals NHS Foundation Trust, Liverpool

The Royal London Hospital, Barts Health NHS Trust, London