Plain-English translation of NCT06224426 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
When patients have a severe stroke caused by a blood clot, doctors perform emergency endovascular therapy—a minimally invasive procedure where a catheter is threaded through blood vessels to remove the clot. During this procedure, patients are put under general anesthesia and breathe through a breathing tube. This trial is testing whether giving patients higher oxygen levels (80%) or lower oxygen levels (30%) during the procedure helps them recover better neurological function in the first 24 hours after treatment.
Doctors are uncertain about the best oxygen level to use during this emergency stroke procedure. Using too much oxygen or too little might affect how well the brain recovers, so this trial aims to find the safest and most effective oxygen level.
You likely qualify if…
You likely don't qualify if…
If you qualify and agree to participate, you will be randomly assigned to receive either high-concentration oxygen (80%) or low-concentration oxygen (30%) during your emergency endovascular stroke procedure under general anesthesia. The oxygen will be delivered through a breathing tube during the entire procedure. Doctors will monitor your brain function and safety, measuring your neurological improvement about 24 hours after the procedure. The trial also tracks safety outcomes like infections and long-term recovery over three months.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
China