Plain-English translation of NCT06225544 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing whether a medication called can safely lower oxalate levels—a harmful salt that builds up in people on kidney dialysis. Researchers want to see if the medication works better than a placebo (a dummy injection) and whether it's well-tolerated in this patient group. The study will track blood levels monthly and also monitor heart health.
People on long-term kidney dialysis often develop dangerously high levels of oxalate, which can damage organs and increase heart problems. This medication has shown promise in other studies, but doctors need to know if it's safe and effective specifically for dialysis patients.
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If you join this study, you will receive either the new medication or a placebo injection and continue your regular dialysis schedule. You'll have blood tests taken before dialysis once a month to measure your oxalate levels, and you'll undergo heart imaging (an echocardiogram) to monitor your heart health. The study lasts several months, and researchers will track how well the treatment works and any side effects.
AI-generated summary from trial data · Jun 15, 2026 · Not medical advice
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