Plain-English translation of NCT06228079 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether adding chemotherapy and immunotherapy after endoscopic surgery helps people with recurrent nasopharyngeal cancer (cancer of the space behind the nose) live longer and stay cancer-free. About half of the 176 participants will have surgery only, while the other half will have surgery followed by the additional medications. Researchers want to know if the extra treatment makes a meaningful difference.
When nasopharyngeal cancer comes back after initial radiation therapy, surgery is often performed to remove the cancer. However, doctors aren't yet certain whether giving additional chemotherapy and immunotherapy after surgery helps prevent the cancer from returning again or improves overall survival.
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If you enroll, you will be randomly assigned to either the surgery-only group or the surgery-plus-treatment group. If you're in the treatment group, you will receive chemotherapy and immunotherapy sessions after your surgery. Both groups will have regular follow-up visits and scans to monitor your health and check for any cancer recurrence over time. The trial involves researchers at multiple hospitals working together to compare how well each approach works.
AI-generated summary from trial data · Aug 5, 2026 · Not medical advice
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