Testing smarter radiation therapy that adapts daily for gynecological cancers

This trial is testing adaptive radiotherapy, a newer approach to treating gynecological cancers like cervical, endometrial, and vaginal cancer. Instead of using the same radiation plan for every treatment session, adaptive radiotherapy takes a new picture of your body before each radiation dose and adjusts the plan right then to match how your body looks that day. This can potentially deliver radiation more precisely to the tumor while sparing healthy tissue nearby.

Standard radiation therapy uses the same treatment plan for all sessions, even though your body changes from day to day (for example, your bladder and rectum fill differently). This trial exists to see whether the treatment can be more effective and safer if doctors adjust the plan each day based on your anatomy at that moment.