Plain-English translation of NCT06234501 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether high-dose vitamin B6 (a form called Pyridoxal-5'-Phosphate) can help reduce sensory sensitivity and anxiety in adults with autism. Some research suggests that vitamin B6 might help the brain work in ways that could ease these challenges. The study will compare people taking the vitamin B6 supplement to people taking a look-alike placebo tablet, to see if there's a real benefit.
Many autistic people experience sensory overload and anxiety that can significantly affect their daily life. This medication is being tested because early research suggests it might help calm the brain's sensory responses, but larger studies are needed to confirm whether it actually works.
You likely qualify if…
You likely don't qualify if…
You would take one tablet by mouth once daily for one month — either the vitamin B6 supplement or a matching placebo tablet. Neither you nor the researchers will know which one you're taking. During this month, you'll be monitored to see if there are any changes in your sensory sensitivity, anxiety, sleep quality, or ability to focus, using questionnaires and simple visual tests.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United Kingdom
University of Reading
Collaborators
INNOPURE
Enrollment target
~40 participants
Started
November 2024
Primary completion
July 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 60 Years
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Dr David T Field, PhD
University of Reading
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.