Plain-English translation of NCT06236464 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying squamous cell cancers that develop in specific areas of the body—the anus, cervix, vulva, and head and neck regions. By collecting and analyzing tissue samples from 170 patients, they hope to understand what causes these cancers at a molecular level and identify new ways to treat them. The research includes growing cancer cells in the lab to test how they respond to experimental drugs.
Squamous cell cancers in these different body areas may share common underlying causes. By studying them together, researchers hope to discover shared weaknesses in the cancer cells that could lead to new treatments that work across multiple cancer types.
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If you join this study, you will donate tumor tissue samples (collected during your planned surgery) and possibly blood samples for analysis. Researchers will study these samples in the laboratory to understand the molecular characteristics of your cancer and test how cancer cells respond to experimental treatments. Some of your tissue cells may be used to grow three-dimensional models in the lab that help researchers predict which new drugs might work best.
AI-generated summary from trial data · Jun 30, 2026 · Not medical advice
Italy
Sponsor
National Cancer Institute, Naples
Enrollment target
~170 participants
Started
September 2023
Primary completion
November 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Maria Lina Tornesello, M.D.
IRCCS I.N.T. "G. Pascale"
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.