Plain-English translation of NCT06236568 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a procedure called hypothermic machine perfusion (HOPE) — a way to treat a donor liver with a specialized machine before transplantation. Researchers want to see if this treatment can help prevent liver cancer from coming back after people receive a transplant, and whether it helps identify which livers are in the best condition for transplant.
When liver cancer patients receive a transplant, their cancer sometimes returns after surgery. This new treatment may reduce that risk by protecting the donor liver from damage that occurs during the transplant process, and by helping doctors identify important markers that predict how well the transplant will work.
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If you join this study, you will be randomly assigned to one of two groups: one group will have their donor liver treated with the machine perfusion device for 90 minutes before transplant, while the other group will receive a standard transplant without this treatment. Researchers will also collect small tissue samples and blood samples before and during your transplant to study how the liver responds, helping them understand how the treatment works.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
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