Plain-English translation of NCT06239649 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing whether a procedure called radiofrequency genicular nerve ablation, performed before knee replacement surgery, can help reduce pain and speed up recovery after the operation. The treatment works by using heat energy to reduce pain signals from nerves around the knee. Researchers want to see if doing this treatment before surgery—rather than waiting until after—helps patients move around sooner and go home faster.
After knee replacement surgery, pain can make it hard for patients to start moving and exercising, which slows down recovery. This treatment has shown promise in reducing knee pain in patients with severe arthritis, so researchers believe doing it before surgery might prevent pain problems after the operation and help patients heal more quickly.
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If you join this study, you will be randomly assigned to either receive the nerve pain treatment before your knee replacement surgery or to have surgery without this treatment beforehand. Both groups will receive standard knee replacement surgery and follow a fast-track recovery program designed to get you moving and home quickly. You'll be monitored after surgery to see how much pain you have, how well you can move, and when you're ready to be discharged from the hospital.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
Turkey (Türkiye)
Sponsor
Pamukkale University
Enrollment target
~60 participants
Started
October 2023
Primary completion
May 2024
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
40 Years – 85 Years
Last updated on clinicaltrials.gov in June 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
HARUN R GUNGOR, MD
Pamukkale University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.