Plain-English translation of NCT06241183 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether an injected medication called famotidine works better than a common over-the-counter antacid liquid (Maalox or Mylanta) for treating severe heartburn and indigestion in people who come to the emergency department. Researchers will measure how quickly and how well each treatment relieves your pain over one hour. The goal is to find out which approach works best for emergency patients with these symptoms.
Many people go to the emergency department with severe heartburn and indigestion, but doctors aren't sure which type of treatment works fastest and best. This study will help doctors decide whether to give patients an injection or an oral liquid antacid when they arrive with this kind of stomach pain.
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You will be randomly assigned to receive either an injection of famotidine or a 30-milliliter dose of oral antacid liquid. Over the next 60 minutes, a study team member will ask you to rate your pain level at 0, 15, 30, 45, and 60 minutes using a simple pain scale. The researchers will also collect information about your symptoms, satisfaction with the treatment, and whether you need any additional pain relief. After one hour, the emergency department doctor can give you additional treatment if needed.
AI-generated summary from trial data · Oct 12, 2026 · Not medical advice
United States