Safety of a kidney-disease antiviral medication in transplant patients

This study looks at the safety of maribavir, an antiviral medication, in adults who have severe kidney disease or kidney failure and developed a persistent cytomegalovirus (CMV) infection after receiving a solid organ or stem cell transplant. Researchers will review existing medical records to understand how well this medication works and what side effects patients experience when they have advanced kidney problems.

Many transplant patients develop hard-to-treat CMV infections, and doctors need to know if this medication is safe to use in patients whose kidneys don't work well — since kidney problems can affect how medications are processed in the body.