Plain-English translation of NCT06244940 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study tests whether whole genome sequencing—a comprehensive genetic test that reads all of a baby's DNA—can identify the cause of congenital heart disease (a heart defect present from birth) in babies diagnosed before birth. Researchers believe this advanced genetic testing can find answers that standard genetic tests miss, helping families understand their baby's condition and prepare for care after birth.
Current genetic testing methods find the cause of congenital heart disease in only about 10% of cases. This study exists to see if more advanced genetic testing can identify the cause in many more babies, giving families answers, better preparation for their baby's birth and early care, and potentially valuable information about other health challenges their baby might face.
You likely qualify if…
You likely don't qualify if…
If you qualify, researchers will collect a small genetic sample during your planned amniocentesis or chorionic villus sampling procedure (no extra procedure needed). They will then use advanced genetic sequencing to analyze your baby's DNA to identify the cause of the heart defect. You may be contacted for follow-up information after your baby is born to help researchers connect genetic findings with your baby's actual health outcomes.
AI-generated summary from trial data · Aug 9, 2026 · Not medical advice
United States