Plain-English translation of NCT06247449 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is investigating whether patients with certain types of early-stage breast cancer—specifically triple negative or HER2-positive disease—have cancer that has spread to the brain without causing any noticeable symptoms. Researchers will use an MRI scan to screen for these hidden brain metastases, and they'll also collect a blood sample to look for tumor DNA markers that might predict who is at highest risk.
Some aggressive breast cancers have a higher chance of spreading to the brain, sometimes silently and without any warning signs. Right now, doctors don't routinely screen for this. This study aims to understand how common this problem really is and whether finding cancer early in the brain—before symptoms appear—could help patients get treatment sooner.
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You will have one brain MRI scan with contrast dye injected into your vein, which takes about 30–45 minutes. You'll also provide one blood sample for testing. After the scan, you'll complete a short questionnaire about how you felt about the screening process. The entire study participation can happen before, during, or after your cancer treatment, as long as it occurs within 18 months of your diagnosis.
AI-generated summary from trial data · Aug 5, 2026 · Not medical advice
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