Testing a cholesterol medication to prevent migraines

Researchers want to confirm whether atorvastatin, a medication commonly used to lower cholesterol, can also help prevent episodic migraines — migraines that happen 4 to 14 times per month. Smaller studies suggested it might work, so this larger trial will test two different doses of the medication against a placebo to see if it truly reduces how often migraines occur.

Many people with episodic migraines struggle to find preventative treatments that work well and are tolerated without serious side effects. Previous small studies hinted that this medication might be safe and effective for migraine prevention, but researchers need a larger study to confirm this finding before it could become a standard treatment option.