Plain-English translation of NCT06248671 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
Researchers want to confirm whether atorvastatin, a medication commonly used to lower cholesterol, can also help prevent episodic migraines — migraines that happen 4 to 14 times per month. Smaller studies suggested it might work, so this larger trial will test two different doses of the medication against a placebo to see if it truly reduces how often migraines occur.
Many people with episodic migraines struggle to find preventative treatments that work well and are tolerated without serious side effects. Previous small studies hinted that this medication might be safe and effective for migraine prevention, but researchers need a larger study to confirm this finding before it could become a standard treatment option.
You likely qualify if…
You likely don't qualify if…
You will first enter a baseline period where you track your migraines in a headache diary for up to 8 weeks to confirm you qualify. If you do, you will be randomly assigned to take either a 40mg dose, a 20mg dose, or a placebo tablet once daily for 84 days (about 12 weeks), while continuing to record your migraines. Throughout the study, you will have clinic visits to monitor your progress and check for any side effects.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
Norway