Plain-English translation of NCT06250972 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This study is testing whether adding radiation therapy to chemotherapy can help people with advanced pancreatic cancer live longer and better control their disease. You would be eligible if your cancer has a high CA19-9 marker (a blood test that tracks pancreatic cancer) and your tumors have responded well to chemotherapy. The researchers want to see if combining both treatments together works better than continuing chemotherapy alone.
Pancreatic cancer is very difficult to treat, and most patients are diagnosed at an advanced stage when the cancer has already spread. While chemotherapy helps some patients, researchers believe that adding radiation therapy—which precisely targets the tumor—might improve survival and help keep the cancer under control longer.
You likely qualify if…
You likely don't qualify if…
You would first receive about 2 to 6 cycles of chemotherapy, and then move on to radiation therapy (most likely intensity-modulated radiation therapy, which precisely targets the tumor). Throughout the study, your doctors will check your progress every four weeks by measuring tumor response and monitoring your blood markers. The study tracks how long you survive and how well your disease is controlled over time.
AI-generated summary from trial data · Jun 15, 2026 · Not medical advice
China
Phase
Large-scale testing
Sponsor
Fudan University
Enrollment target
~210 participants
Started
May 2024
Primary completion
May 2027
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in August 2025.
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Central contact
Ying Yang, MD
Fudan University
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