Plain-English translation of NCT06253715 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether a newer, shorter treatment regimen using , , , and can cure tuberculosis in children just as well as the standard longer treatment. Currently, children with tuberculosis typically receive treatment for several months, but researchers want to see if this new combination of medications can work in just 8 weeks, making treatment easier for families.
Tuberculosis treatment in children currently takes many months, which can be hard for families to complete and increases the chance that children will stop taking their medications before they're fully cured. A shorter, effective treatment would help more children complete their therapy and reduce the burden on families.
You likely qualify if…
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If you join this trial, you will be randomly assigned to receive either the new 8-week treatment regimen with four daily medications or the standard longer treatment that lasts 4 to 6 months. You will visit the study clinic regularly so doctors can check how well the treatment is working, monitor your health, and make sure you're not having any side effects. Your parent or guardian will help you take your medications every day, and the study team will support you throughout the entire treatment period.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
India
Indonesia
Mozambique
South Africa