Plain-English translation of NCT06266260 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing a new way to measure pressure inside your liver using a special ultrasound procedure called endoscopic ultrasound. Doctors want to see if this new method can help them understand how well your blood pressure-lowering medications are working and predict which patients might develop serious bleeding or other complications related to liver disease.
When the liver is badly scarred, blood pressure builds up and can cause life-threatening bleeding. Doctors currently use an invasive test to measure this pressure, but it's uncomfortable and not always available. This study explores whether a gentler ultrasound method could give doctors the same important information to guide treatment decisions.
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You will have ultrasound scans performed at the start of the study and again after your blood pressure medication is adjusted to the right dose. You'll visit the clinic every 2 to 3 months for follow-up appointments to check how you're doing and watch for any complications. The study will also collect small samples like blood and stool to look for other signs of how well the treatment is working.
AI-generated summary from trial data · Jun 8, 2026 · Not medical advice
Italy
Sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Enrollment target
~50 participants
Started
September 2023
Primary completion
April 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 99 Years
Last updated on clinicaltrials.gov in March 2025.
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Central contact
Francesco Santopaolo, MD
Fondazione Policlinico A. Gemelli IRCCS, Rome
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.