Plain-English translation of NCT06266403 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand how amyotrophic lateral sclerosis (ALS) affects the way people speak during real conversations. This study will ask people with ALS and people without ALS to complete four different speaking tasks — some alone and some while talking with an unfamiliar partner — so researchers can identify speech patterns that are specific to ALS.
People with ALS often experience changes in their speech, but we don't fully understand how these changes show up differently depending on whether someone is speaking alone or having a conversation. This research could help doctors better recognize and support speech changes in people living with ALS.
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You would complete four different speaking tasks from home using a tablet and audio recorder provided by the researchers. One task involves speaking clearly on your own; the other three involve having structured conversations with an unfamiliar partner. A researcher will explain everything via video call, and your speech will be recorded. The entire study involves one session of these tasks, all completed at home.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
United States
Sponsor
Penn State University
Enrollment target
~300 participants
Started
November 2024
Primary completion
February 2029
Age range
18 Years – 90 Years
Last updated on clinicaltrials.gov in January 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Anne Olmstead, Ph.D.
The Pennsylvania State University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.