Plain-English translation of NCT06266403 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand how ALS affects the way people speak during real conversations. This study will have people with ALS and people without ALS complete four different speaking tasks — one alone and three while talking with someone they've never met — so scientists can see exactly how and why ALS changes speech in social situations.
ALS damages the muscles people use to speak, but scientists don't fully understand how this affects communication during actual conversations versus when someone speaks alone. This research will help doctors and speech therapists better support people with ALS in everyday communication.
You likely qualify if…
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You will complete four speaking tasks from home using a tablet and audio recorder provided by the study team. A researcher will explain everything to you via video call, and you'll talk with an unfamiliar person for some of the tasks while your speech is recorded. The entire study takes place remotely, so you won't need to travel to a clinic.
AI-generated summary from trial data · Aug 10, 2026 · Not medical advice
United States
Sponsor
Penn State University
Enrollment target
~300 participants
Started
November 2024
Primary completion
February 2029
Age range
18 Years – 90 Years
Last updated on clinicaltrials.gov in August 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Anne Olmstead, Ph.D.
The Pennsylvania State University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.