Plain-English translation of NCT06266494 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing two different approaches to prevent infection in people with severe frostbite injuries: aloe vera applied directly to the wound, and special silver-based dressings. The study also evaluates how well an antibiotic called works for treating frostbite wounds that have become infected, and how severe cold injuries might affect how quickly your body processes medications.
Frostbite injuries are at high risk for serious infections that can be difficult to treat. Doctors need better ways to prevent these infections from developing in the first place, and need to understand which antibiotics work best when infections do occur.
If you join this study, you'll receive one of two wound treatments while hospitalized: either aloe vera applied twice daily or special silver dressings changed every 4 days. If your wound becomes infected, you may receive a single dose of the antibiotic medication through an IV. Researchers will monitor your wound healing, check for infection, and study how your body processes the medication over time.
AI-generated summary from trial data · Aug 20, 2026 · Not medical advice
United States