Stress-reducing breathing training alongside bladder cancer chemotherapy

This trial is testing whether a stress-reducing breathing technique called heart-rate variability biofeedback can help people with muscle-invasive bladder cancer feel better during their chemotherapy treatment. You would learn deep, paced breathing exercises guided by a heart-rate monitor, and practice them at home for three months alongside your standard cancer treatment. Researchers want to see if this breathing program reduces inflammation, improves sleep, helps with thinking clearly, and makes chemotherapy easier to tolerate.

Chemotherapy for bladder cancer is very tough on the body and mind—it causes stress, pain, and side effects that can hurt quality of life. This trial exists to find out whether a simple, low-cost breathing technique can help your body handle treatment better and may even improve how well the treatment works.