Plain-English translation of NCT06272461 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether Lidocaine or Ketamine—two medications given through an IV during your colon or rectal cancer surgery—can better reduce inflammation in your body after the operation. Researchers believe that controlling inflammation early might help you recover better. You would receive one of these two medications as a continuous infusion for 24 hours during and after your surgery, and your blood would be tested before and after to measure inflammation levels.
Cancer surgery can trigger a strong inflammatory response in the body, which may slow healing and cause complications. This study wants to find out whether giving this medication during surgery can reduce that inflammation and potentially improve how well patients recover.
You likely qualify if…
You likely don't qualify if…
You would be randomly assigned to receive either Lidocaine or Ketamine through an IV during your colorectal cancer surgery. The medication would start with a single dose before anesthesia and then continue as a steady infusion for 24 hours. Your blood would be drawn before your surgery begins and again 24 hours after surgery to measure inflammation levels. Your surgery should take no longer than 5 hours, and you should not experience any severe complications during the procedure.
AI-generated summary from trial data · Jun 30, 2026 · Not medical advice
Tunisia