Plain-English translation of NCT06273072 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Asthma research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether metformin hydrochloride, a medication commonly used to treat type 2 diabetes, might also help people with asthma that isn't well-controlled, especially if they are overweight or obese. Researchers believe this medication might reduce asthma symptoms and attacks in this group of people. Half of participants will take the actual medication daily, and half will take a placebo (a pill that looks identical but has no active ingredient) for six months.
Many people with asthma who are overweight or obese continue to have symptoms even when taking their regular asthma inhalers. This study explores whether this medication—which affects how the body processes blood sugar and inflammation—might help control asthma better in this population.
You likely qualify if…
You likely don't qualify if…
If you enroll, you'll be randomly assigned to take either the medication or a placebo pill once daily for six months. You'll have regular check-in visits via telemedicine (video call) to make sure the medication is safe for you and to see how well you're taking it. Your asthma will be measured at the start, and again at three months and six months to see if the treatment is helping. The whole study lasts six months and involves visits from home.
AI-generated summary from trial data · Jun 29, 2026 · Not medical advice
United States