Plain-English translation of NCT06278506 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Kidney Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study compares two established treatments for small kidney cancers: surgical removal (called partial nephrectomy) versus ablative treatment, which uses heat or freezing to destroy the tumor. Researchers want to understand which approach leads to fewer complications, shorter hospital stays, and equally good long-term cancer control.
Many small kidney tumors are now found by accident during imaging for other reasons. While both surgery and heat-based treatments are used in practice, no large comparison study has directly tested which is safer and more effective for patients. This trial aims to answer that question.
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If you enroll, you will be randomly assigned to receive either surgery to remove part of your kidney or heat-based ablation treatment to destroy the tumor. You will be hospitalized for the procedure and monitored afterward. The study will track your recovery, any complications, how well your kidneys work over time, and whether the cancer returns, with follow-up visits and imaging over the coming years.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
Sweden
Sponsor
Karolinska University Hospital
Enrollment target
~300 participants
Started
January 2024
Primary completion
December 2027
Age range
18 Years – 99 Years
Last updated on clinicaltrials.gov in February 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Anders Kjellman, MD, PhD
Karolinska University Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.