Plain-English translation of NCT06279351 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether thalidomide, a medication, can make standard colorectal cancer treatment more effective for patients with advanced cancer on the left side of the colon. Right now, doctors treat this type of cancer with a combination of chemotherapy and a targeted drug called cetuximab. Researchers want to see if adding thalidomide to this standard treatment helps patients respond better and live longer.
Current treatments for advanced colorectal cancer help some patients, but doctors are looking for ways to improve outcomes. This trial is exploring whether the medication can boost how well existing treatments work, which could help more patients benefit from their cancer care.
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If you join this trial, you will receive either the standard cancer treatment alone or the standard treatment plus the new medication (thalidomide). You will visit the hospital regularly for chemotherapy infusions, blood tests, and scans to monitor how well the treatment is working. The trial also involves blood draws to measure certain immune system markers that may help explain how the medication works.
AI-generated summary from trial data · Jul 3, 2026 · Not medical advice
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