Plain-English translation of NCT06284343 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is creating a new tool to help doctors identify which women with gynecological cancer (ovarian, uterine, cervical, vaginal, or vulvar cancer) are at greatest risk of developing blood clots during chemotherapy treatment. Researchers will collect medical information, blood tests, and genetic data from about 1,800 women to build and test this prediction tool. The goal is to help doctors prevent blood clots more effectively in this patient population.
Women with gynecological cancer face a higher risk of blood clots during chemotherapy than other cancer patients, and current prediction tools don't work as well for them. This study aims to create a better, more tailored tool to identify which patients need blood-clot prevention treatment, potentially reducing serious complications and improving survival.
You likely qualify if…
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You will be enrolled when you start a new chemotherapy treatment and followed for the entire duration of that treatment—typically around 12 months or longer. Researchers will collect your medical history, perform routine blood tests, and assess genetic factors related to blood clotting. You may receive blood-clot prevention medication if your risk score is high enough. Throughout your treatment, doctors will monitor you for any blood clots, bleeding problems, or other health events and record the outcomes.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
Italy
Sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Collaborators
Fondazione Umberto Veronesi
Enrollment target
~1,800 participants
Started
April 2024
Primary completion
September 2026
Age range
18 Years and older
Sex
Female only
Last updated on clinicaltrials.gov in September 2024.
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Central contact
Roberto Pola, PhD; MD
Agostino Gemelli University Polyclinic Foundation IRCCS
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.